DNA repair protein BRCA1 implicated in cognitive function and dementia

November 30th, 2015 | Posted by admin in Uncategorized

Researchers have shown for the first time that the protein BRCA1 is required for normal learning and memory and is depleted by Alzheimer's disease. BRCA1 is a key protein involved in DNA repair, and mutations that impair its function increase the risk for breast and ovarian cancer. The new study demonstrates that Alzheimer's disease is associated with a depletion of BRCA1 in neurons and that BRCA1 depletion can cause cognitive deficits.
Source: Medicine Science Daily

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